发明名称 |
COMBINATION THERAPIES USING HDAC INHIBITORS |
摘要 |
The present invention pertains to a method for treating cancer, such as lung cancer, multiple myeloma, lymphoma, and epithelial ovarian cancer, comprising the administration to a patient in need thereof a first amount or dose of a histone deacetylase (HDAC) inhibitor, such as PXD-101, and a second amount or dose of another chemotherapeutic agent, such as dexamethasone or 5-fluorouracil, or an epidermal growth factor receptor (EGFR) inhibitor, such as TarcevaÚ, wherein the first and second amounts or doses together comprise a therapeutically effective amount. |
申请公布号 |
WO2006082428(A2) |
申请公布日期 |
2006.08.10 |
申请号 |
WO2006GB00391 |
申请日期 |
2006.02.03 |
申请人 |
TOPOTARGET UK LIMITED;CURAGEN CORPORATION;LICHENSTEIN, HENRI;JEFFERS, MIKE;QIAN, XIAOZHANG;SEHESTED, MAXWELL;PETERSEN, KAMILLE, DUMONG;RITCHIE, JAMES |
发明人 |
LICHENSTEIN, HENRI;JEFFERS, MIKE;QIAN, XIAOZHANG;SEHESTED, MAXWELL;PETERSEN, KAMILLE, DUMONG;RITCHIE, JAMES |
分类号 |
A61P35/00;A61K31/00;A61K31/18;A61K31/282 |
主分类号 |
A61P35/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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