IMPROVING SURVIVAL AND PROLIFERATION OF CD4+ AND CD25+ T CELLS

摘要

The invention relates to a method of growing CD4+,CD25+ T cells in vitro, comprising culturing CD4+,CD25+ T cells under conditions that inhibit the effect of nitric oxide production on the survival and/or proliferation of CD4+,CD25+ T cells. The invention also relates to methods of increasing tolerance in a subject by administering CD4+, CD25+ T cells grown in vitro.