发明名称 METHOD FOR EVALUATING TOXICITY OF BACTERIAL ANTIGENS
摘要 FIELD: microbiology, immunology. ^ SUBSTANCE: the culture of Paramecium caudatum infusorias should be supplemented with a tested antigen in different dilutions and kept for 3 min at a room temperature to count the number of contractions of excretory vacuoles/min in 6-7 infusorias, detect toxic impact of bacterial antigen according to suppression degree of infusorial excretory function, and toxic concentration is stated upon at antigen concentration that decreases the number of contractions of infusorial excretory vacuoles against the control by 50%. Thus, a highly sensitive and rapid method for evaluating toxicity of bacterial antigens has been successfully elaborated. ^ EFFECT: higher accuracy of evaluation. ^ 5 dwg, 1 ex, 2 tbl
申请公布号 RU2281507(C2) 申请公布日期 2006.08.10
申请号 RU20040133598 申请日期 2004.11.17
申请人 VOLGOGRADSKIJ NAUCHNO-ISSLEDOVATEL'SKIJ PROTIVOCHUMNYJ INSTITUT 发明人 ZHUKOVA SVETLANA IVANOVNA;ADEL'SHIN FARID KASIMOVICH;KHRAPOVA NATAL'JA PETROVNA;PIVEN' NIKOLAJ NIKOLAEVICH;PROSHINA OL'GA BORISOVNA;ZASJADKINA ANNA VLADIMIROVNA;PLEKHANOVA NATAL'JA GENNADIEVNA
分类号 G01N33/483 主分类号 G01N33/483
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