СПОСОБ ПОЛУЧЕНИЯ ПУРИНОВЫХ НУКЛЕОЗИДОВ И НУКЛЕОТИДОВ МЕТОДОМ ФЕРМЕНТАЦИИ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ,ПРИНАДЛЕЖАЩИХ К РОДУ ESCHERICHIA ИЛИ BACILLUS

摘要

FIELD: biotechnology. ^ SUBSTANCE: method for production of purine nucleosides and purine nucleotides, in particular 5'-inosinic acid is disclosed. Claimed method includes using of bacterium belonging to genus Esherichia or genus Bacillus. Production of purine nucleosides and purine nucleotides by said bacterium is increased due to increased activity of YdhL pritein. Also disclosed is amino acid sequence of YdhL pritein from Bacillus amyloliquefaciens and gene encoding thereof. ^ EFFECT: method for industry scale production of nucleosides and nucleotides. ^ 25 cl, 2 dwg, 6 tbl, 9 ex