DEFORMING SURFACE OF DRUG ELUTING COATING TO ALTER DRUG RELASE PROFILE OF A MEDICAL DEVICE

摘要

A method is provided for altering a drug release profile of a coating of a medical device. The method includes determining the drug release profile of the coating of the medical device; determining an increased surface area necessary to alter the drug release profile to an altered drug release profile; and increasing a surface area of the coating of the medical device to obtain the altered drug release profile. A method is provided for improving a drug release profile of a coating of a medical device. The method includes determining an expected drug release profile of the coating of the medical device using first process parameters of a coating method; determining an increased surface area necessary to obtain an improved drug release profile; and altering the first process parameters to second process parameters of the coating method to achieve the increased surface area. A device is provided for altering a drug release profile of a coating of a medical device. The device includes an arrangement adapted to hold the medical device and an arrangement adapted to indent a surface area of the coating.