METHOD FOR PRODUCTION OF HEPATOTHROPIC ARTICHOKE EXTRACT-BASED POLYPHENOL PHARMACEUTICAL AGENT

摘要

FIELD: pharmaceutical industry, in particular production of hepatothropic drug based on artichoke polyphenols. ^ SUBSTANCE: claimed method includes breakage of fresh artichoke leaves, treatment with hot steam for certain time; two-step extraction with hot water under specific conditions, extract separation from solvent cake, concentration of artichoke aqueous extract in vacuum to produce syrup-like extract. Obtained syrup-like extract is blended with filler, detacher and lubricant in specific component ratio. ^ EFFECT: method of increased yield; biologically active substances of improved stability; reduced raw material and extractant consumption; capsulated hepatothropic drug with high therapeutic activity and prolonged storage time. ^ 10 cl, 8 ex