| 摘要 |
FIELD: medicine, mycology. ^ SUBSTANCE: invention proposes a medicinal agent against human candidosis that comprises an active component as inactivated cytoplasm fraction form the fungus strain Candida albicans and a solvent. An active component represents fungus cellular walls and cytoplasm after culturing the fungus strain Candida albicans 253 for 28-36 h and shows the fungus cells concentration 1.85 x 108 - 2.5 x 108/1 cm3 of distilled water, immunogenicity index is 6-9%, the content of lipids is up to 0.2%, polysaccharide is 50-76%, peptides with molecular mass > 10 kDa is 80-87%. The agent comprises formalin as an inactivating agent and distilled water as a solvent in the following ratio of components, wt.-%: active component as cellular walls and cytoplasm from the fungus strain Candida albicans 253 with the concentration of fungus spores 1.85 x 108 - 2.5 x 108/1 cm3 of distilled water, 2.0-2.7; formalin, 0.1-0.15, and water, the balance. Invention provides the effective and safety agent against human candidosis. Invention can be used in treatment of candidosis. ^ EFFECT: enhanced effectiveness and valuable medicinal properties of agent. ^ 4 ex |
