A method for screening for variant peptides uses mass spectrometry (MS). A system and a kit may be used for performing the method. Proteins in a sample are digested to form a defined series of peptides. The defined series of peptides are ionized. The ionized species are subjected to collision induced dissociation. Species of known mass/charge ratio are detected to confirm the presence of the protein variant in the original sample.
申请公布号
CA2596010(A1)
申请公布日期
2006.08.10
申请号
CA20062596010
申请日期
2006.02.01
申请人
KING'S COLLEGE LONDON;GUY'S & ST. THOMAS' NHS FOUNDATION TRUST
发明人
TURNER, CHARLES;DANIEL, YVONNE ANNE;DALTON, RAYMOND NEIL