| 发明名称 |
Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE) |
| 摘要 |
The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of beta-secretase, also known as beta-site cleaving enzyme and BACE.
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| 申请公布号 |
US2006178383(A1) |
申请公布日期 |
2006.08.10 |
| 申请号 |
US20050197615 |
申请日期 |
2005.08.04 |
| 申请人 |
BISCHOFF FRANCOIS P;BRAEKEN MIRIELLE;ALOYSIUS PIETERS SERGE M;MERCKEN MARK H;DE WINTER HANS LOUIS J;BERTHELOT DIDIER J |
发明人 |
BISCHOFF FRANCOIS P.;BRAEKEN MIRIELLE;ALOYSIUS PIETERS SERGE M.;MERCKEN MARK H.;DE WINTER HANS LOUIS J.;BERTHELOT DIDIER J. |
| 分类号 |
A61K31/517;C07D403/02 |
主分类号 |
A61K31/517 |
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