PREVENTIVE OR THERAPEUTIC AGENT FOR HERPESVIRUS-RELATED DISEASE

摘要

[PROBLEMS] To provide a medicine, particularly a pharmaceutical composition useful for preventing or treating a variety of diseases caused by infection of a virus of the Herpesviridae family. [MEANS FOR SOLVING PROBLEMS] The present invention relates to an anti-herpesvirus agent characterized by combining a helicase-primase inhibitor with a polymerase inhibitor. By combining the helicase-primase inhibitor with the polymerase inhibitor having different action mechanisms, the anti-herpesvirus agent of the present invention achieves a dramatically superior anti-herpesvirus action compared with conventional administration of a polymerase inhibitor alone. Therefore, it is particularly effective in a case in which a sufficient therapeutic effect cannot be achieved only with a polymerase inhibitor. Further, the doses of both agents can be kept low, therefore it is also possible to perform treatment by lowering the effect of an adverse reaction to be concerned.