| 发明名称 |
ЦИС-2, 4, 5-ТРИАРИЛ-ИМИДАЗОЛИНЫ |
| 摘要 |
The present invention provides compounds according to formula (I ) having the designations provided herein, and pharmaceutically acceptable salts and esters thereof These compounds inhibit the interaction of MDM2 protein with a p53-like peptide and have antiproliferative activity. |
| 申请公布号 |
RU2006100730(A) |
申请公布日期 |
2006.08.10 |
| 申请号 |
RU20060100730 |
申请日期 |
2004.06.08 |
| 申请人 |
Ф.ХОФФМАНН-ЛЯ РОШ АГ (CH) |
发明人 |
ХЕЙЛИ Грегори Джей (US);КОН Норман (US);ЛЮ Эмили Айцунь (US);СИМОНСЕН Клаус Б. (US);ВУ Бинх Тханх (US);УЭББЕР Стивен Эван (US) |
| 分类号 |
C07D233/22;C07D233/36;C07D233/54;C07D401/06;C07D401/10;C07D401/12;C07D401/14;C07D403/06;C07D403/10;C07D403/12;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D491/10 |
主分类号 |
C07D233/22 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
