BACTERIUM STRAIN Escherichia coli USEFUL IN NORMALIZATION OF GASTROINTESTINAL TRACT PHYSIOLOGICAL ACTIVITY, PROBIOTIC COMPOSITION FOR NORMALIZATION OF GASTROINTESTINAL TRACT PHYSIOLOGICAL ACTIVITY (VARIANTS), METHOD FOR PRODUCTION THEREOF AND METHOD FOR CULTURING OF BACTERIUM STRAIN Escherichia coli

摘要

FIELD: biotechnology, in particular strain of probiotic microorganism and probiotic composition. ^ SUBSTANCE: invention relates to composition for normalization of gastrointestinal tract physiological activity containing specific strain Escherichia coli BU-230-98 as active ingredient or therapeutically effective amount of bacteria of said strain in combination with at least one volatile fraction of plant extract. Probiotic composition is obtained by suspending of therapeutically effective amount of bacteria of strain E.coli BU-230-98 in volatile fraction of plant extract, obtained by water extraction. Abovementioned volatile fraction is obtained by steam distillation of said plant extract under pressure lower atmospheric one and at bath temperature of at most 38°C. Strain Escherichia coli BU-230-98 is cultured on broth up to optical density of 15-30 at 650 nm that is adequate to concentration of 1010-1011 CFU/ml. Foodstuff contains at least one product obtained from milk and includes bacteria of abovementioned strain E.coli. ^ EFFECT: effective composition for treatment and prophylaxis of various gastrointestinal disorders, weight increment and immunostimulation for mammalian and poultry. ^ 44 cl, 1 dwg, 4 tbl, 24 ex