发明名称 |
AZASUGAR DERIVATIVES, HEPARANASE INHIBITORS, METHOD FOR PREPARING SAME, COMPOSITIONS CONTAINING SAME, USE THEREOF |
摘要 |
The invention concerns heparanase inhibiting compounds of general formula (I) wherein R represents a hydrogen atom, an hydroxyl radical, a -OSO<SUB>3</SUB>- radical, a -O-(C<SUB>1</SUB>-C<SUB>5</SUB>)alkyl radical or an -O- aralkyl radical; Z represents a COO<SUP>-</SUP> radical or a hydroxyl radical; X represents -OH or a saccharide unit of formula A, Y represents H, C<SUB>1</SUB>-C<SUB>5</SUB> alkyl or a saccharide unit of formula D; in free form or in the form of pharmaceutically acceptable salts formed with a base or an acid as well as in the form of solvates or hydrates. The derivatives of the invention are useful as medicines. |
申请公布号 |
WO2006021653(A3) |
申请公布日期 |
2006.08.10 |
申请号 |
WO2005FR01851 |
申请日期 |
2005.07.20 |
申请人 |
SANOFI-AVENTIS;DRIGUEZ, PIERRE, ALEXANDRE;PETITOU, MAURICE |
发明人 |
DRIGUEZ, PIERRE, ALEXANDRE;PETITOU, MAURICE |
分类号 |
C07H3/06;A61K31/7008;A61K31/702;A61P35/00;C07H5/06 |
主分类号 |
C07H3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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