发明名称 N-substituted pyrrolidin derivatives as dipeptidyl peptidase IV inhibitors
摘要 The present invention relates to compounds of formula (I) wherein R<SUP>1</SUP>, R<SUP>2</SUP>, and X are as defined in the description and claims, and pharmaceutically acceptable salts thereof. The compounds are useful for the treatment and/or prophylaxis of diseases which are associated with DPP IV, such as diabetes, particularly non-insulin dependent diabetes mellitus, and impaired glucose tolerance.
申请公布号 AU2002338902(B2) 申请公布日期 2006.08.03
申请号 AU20020338902 申请日期 2002.10.18
申请人 F. HOFFMAN-LA-ROCHE AG 发明人 HOLGER KUEHNE;MARKUS BOEHRINGER;BERND MICHAEL LOEFFLER;RAMAKANTH SARABU;DANIEL HUNZIKER;HANS PETER WESSEL
分类号 A61K31/401;A61K;A61K31/40;A61K31/4025;A61K31/403;A61K31/404;A61K31/4045;A61K31/4155;A61K31/416;A61K31/4178;A61K31/4184;A61K31/4196;A61K31/422;A61K31/423;A61K31/4245;A61K31/427;A61K31/428;A61K31/437;A61K31/4439;A61K31/444;A61K31/454;A61K31/4709;A61K31/497;A61K31/506;A61K31/5355;A61P1/00;A61P1/04;A61P3/04;A61P3/10;C07D;C07D207/16;C07D401/12;C07D401/14;C07D403/12;C07D403/14;C07D409/14;C07D413/12;C07D413/14;C07D417/12;C07D417/14;C07D471/04;C07D513/04 主分类号 A61K31/401
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