METHOD FOR OBTAINING MICRO- AND NANO-DISPERSE SYSTEMS

摘要

The invention relates to a method for obtaining micro- and nanodisperse systems. In particular, it relates to a method that allows said systems, such as liposomes, emulsions and suspensions, to be obtained with a size of less than 50mm, and preferably less than 1mm, and with improved stability properties over time, which includes the stages of a) Dissolving or suspending a compound C in a fluid A, to obtain a mixture A, in the form of a solution or dispersion; b) Thermostatising said mixture A to a temperature of between -50°C and 200°C; c) Adding a fluid B to mixture A until a pressure P is obtained; and it is characterised in that in said stage (c) formation of the solution AB occurs and because it includes, d) Reducing the pressure of solution AB to a pressure lower than or equal to 100 bars, and then e) Adding a fluid E, in which fluid A is miscible and in which compound C is partially or totally insoluble at atmospheric pressure, with said fluid E acting as a crystallisation interruption agent.