发明名称 |
COMPOSITION FOR TREATING IMMUNITY-RELATED DISEASE AND METHOD |
摘要 |
<P>PROBLEM TO BE SOLVED: To provide a method for diagnosing or treating the immunity-related diseases of a mammal including human being. <P>SOLUTION: A polypeptide having a specific amino acid sequence and having a T-lymphocyte proliferation-inhibiting activity. A nucleotide sequence encoding PRO polypeptide. A vector containing the sequence. A host containing the vector and expressing the polypeptide. A chimera molecule with an epitope tag sequence or immune globulin different kind polypeptide, fused with the polypeptide. An antibody to be specifically bound to the polypeptide, or its fragment. These substances are useful for medicinal compositions or kits for diagnosing immune-related diseases. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
申请公布号 |
JP2006197937(A) |
申请公布日期 |
2006.08.03 |
申请号 |
JP20060013034 |
申请日期 |
2006.01.20 |
申请人 |
GENENTECH INC |
发明人 |
SHERMAN FONG;GODDARD AUDREY;GODOWSKY PAUL J;GRIMALDI J CHRISTOPHER;GURNEY AUSTIN L;HILLAN KENNETH J;TUMAS DANIEL;WATANABE COLIN K;WOOD WILLIAM I;ZHANG ZEMIN |
分类号 |
C12N15/09;G01N33/50;A61K38/00;A61K38/17;A61K39/00;A61K39/395;A61K45/00;A61P1/04;A61P1/16;A61P3/10;A61P5/14;A61P7/04;A61P7/06;A61P9/00;A61P11/00;A61P11/02;A61P11/06;A61P13/12;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/02;A61P21/00;A61P25/00;A61P25/02;A61P25/28;A61P29/00;A61P31/04;A61P31/14;A61P31/20;A61P35/00;A61P37/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07K14/47;C07K16/00;C07K16/18;C07K16/46;C07K19/00;C12N1/19;C12N1/21;C12N5/10;C12N15/12;C12N15/62;C12P21/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/15;G01N33/53 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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