摘要 |
The present invention refers to a process for preparing a compound of general formula (A), as reported in the description, wherein R is a radical of naproxen or bromonaproxen and R<SUB>1</SUB>-R<SUB>12 </SUB>are hydrogen or alkyl groups, m, n, o, q, r and s are each independently an integer from 0 to 6, and p is 0 or 1, and and X is O, S, SO, SO<SUB>2</SUB>, NR<SUB>13 </SUB>or PR13 or an aryl, heteroaryl group, said process comprising reacting a compound of formula (B) <?in-line-formulae description="In-line Formulae" end="lead"?>R-COOZ (B) <?in-line-formulae description="In-line Formulae" end="tail"?> wherein R is as defined above and Z is hydrogen or a cation selected from: Li+, Na+, K+, Ca++, Mg++, tetralkylammonium, tetralkylphosphonium, with a compound of formula (C), as reported in the description, wherein R1-R12 and m, n, o, p, q, r, s are as defined above and Y is a suitable leaving group.
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