摘要 |
A device for producing rapid temperature changes around microscopic samples comprises two hollow channels ( 5,6 ) positioned at the same plane but at an angle to each other, FIG. 1 . Streams of solutions ( 9, 10 ) flowing from the respective channels are maintained at different temperatures through heating or cooling elements ( 7, 8 ) conducting heat to or away from the channels. Initially, the sample ( 12 ) is surrounded by stream ( 9 ) at initial temperature, FIG. 3 . After flow of this stream stops, the sample is surrounded by another stream ( 10 ) at a different temperature. This results in the temperature change, which does not depend on the volume of liquid in the system and on the size of heating or cooling elements.
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