发明名称 |
Synthesis and characterization of novel systems for guidance and vectorization of molecules of therapeutic interest towards target cells |
摘要 |
A method for preparing a grafted homodetic cyclopeptide froming a framework that defines a grafted upper face and grafted lower face, including synthesizing a linear peptide from modified or unmodified amino acids, some of which carry orthogonal protective groups; intramolecular cyclizing the resulting protected linear peptide; substituting some or all of orthogonal protective groups with a protected precursor; and grafting at least one molecule of interest onto one and/or the other face of the framework via an oxime bond.
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申请公布号 |
US2006173160(A1) |
申请公布日期 |
2006.08.03 |
申请号 |
US20050528320 |
申请日期 |
2005.10.11 |
申请人 |
DUMY PASCAL;FAVROT MARIE-CHRISTINE;BOTURYN DIDIER;COLL JEAN-LUC |
发明人 |
DUMY PASCAL;FAVROT MARIE-CHRISTINE;BOTURYN DIDIER;COLL JEAN-LUC |
分类号 |
C07K1/02;A61K38/00;A61K38/12;A61P35/00;C07K7/64;C07K9/00 |
主分类号 |
C07K1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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