发明名称 |
Stent coating for eluting medication |
摘要 |
<p>A vascular stent comprising a drug-eluting outer layer of a porous sputtered columnar metal having each column capped with a biocompatible carbon-containing material is described. This is done by placing the stent over a close-fitting mandrel and rotating the assembly in a sputter flux. The result is a coating that is evenly distributed over the outward-facing side of the stent's wire mesh while preventing the sputtered columnar coating from reaching the inward facing side where a smooth hemocompatible surface is required. The stent is then removed from the mandrel, exposing all surfaces, and finally coated with a layer of carbon such as amorphous carbon or diamond-like carbon. The carbonaceous coating enhances biocompatibility without preventing elutriation of a therapeutic drug provided in the porosity formed between the columnar structures. The result is a stent that is adapted to both the hemodynamic and the immune response requirements of its vascular environment.</p> |
申请公布号 |
EP1685861(A2) |
申请公布日期 |
2006.08.02 |
申请号 |
EP20060001891 |
申请日期 |
2006.01.30 |
申请人 |
GREATBATCH, INC. |
发明人 |
O'BRIEN, ROBERT, C.;FRYSZ, CHRISTINE, A. |
分类号 |
A61L31/08;A61L31/14;A61L31/16 |
主分类号 |
A61L31/08 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|