发明名称 |
TARGETING COMPOSITIONS AND PREPARATION THEREOF |
摘要 |
<p>The present invention relates to targeted cancer therapy and tumour imaging, and concerns specifically new derivatives of small matrix metalloproteinase inhibitor peptides. These new derivates are the hydrophilic peptides GRENYHGCTTHWGFTLC and derivates thereof. These peptides have an increased solubility and may be used in the preparation of targeting compositions together with suitable linker molecules such as PEG. Such targeting compositions are useful in therapeutics and imaging liposome compositions for cancer treatment and diagnostics.</p> |
申请公布号 |
EP1685153(A1) |
申请公布日期 |
2006.08.02 |
申请号 |
EP20040791442 |
申请日期 |
2004.10.15 |
申请人 |
CTT CANCER TARGETING TECHNOLOGIES OY |
发明人 |
ZHU, YING;VALTANEN, HELI;KAUKINEN, SAMI;PENATE MEDINA, OULA;SIMPURA, ILKKA |
分类号 |
C07K7/64;A61K38/00;A61K38/12;A61K38/55;A61K47/48;A61P35/00;C07K7/06;C07K7/08;C07K14/81 |
主分类号 |
C07K7/64 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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