This invention relates to novel complexes that can be used to target tumor cells. The complexes include a ligand that can bind metal ions including radioactive lanthanide ions. The complexes can mimic alpha<SUB>nu</SUB>beta3 integrin receptor antagonists and deliver the complexed radioactive metals to the tumor cells.
申请公布号
EP1684809(A1)
申请公布日期
2006.08.02
申请号
EP20040789423
申请日期
2004.09.30
申请人
SEMAFORE PHARMACEUTICALS, INC.
发明人
GARLICH, JOSEPH, R.;SUHR, ROBERT, G.;PATTERSON, MARY