发明名称 NOVEL GLYCOPROTEIN AND MEDICINAL COMPOSITION CONTAINING THE SAME
摘要 A novel glycoprotein having (a) a molecular weight of approximately 60 kDa and (b) a ratio of a carbohydrate content to a protein content of 16.4:1.0 (carbohydrate: protein) is disclosed. The glycoprotein can be prepared by (1) extracting Tricholoma matsutake with an alkaline solution or hot water, (2) adsorbing the resulting extract by an anion exchange resin, (3) eluting the adsorption fraction from the anion exchange resin with an eluting solution, and (4) obtaining a fraction having a molecular weight of 50 to 70 kDa by gel filtration. The glycoprotein is useful as the active ingredient for an immune enhancing agent, an agent for promoting a recovery from stress, or an antitumor agent.
申请公布号 EP1686136(A1) 申请公布日期 2006.08.02
申请号 EP20040817163 申请日期 2004.10.13
申请人 KUREHA CORPORATION 发明人 MATSUNAGA, KENICHI;HOSHI, HIROTAKA
分类号 C07K14/75;A61K38/00;A61P35/00;A61P37/04;A61P43/00;C07K14/375;C12P21/00 主分类号 C07K14/75
代理机构 代理人
主权项
地址