Stable immunogenic product comprising antigenic heterocomplexes

摘要

Disclosed herein is a stable immunogenic product for the induction of antibodies raised against one or more antigenic proteins in a subject, wherein it comprises protein immunogenic heterocomplexes consisting of associations between (i) antigenic protein complexes and (ii) carrier protein molecules and in that less than 40% of the antigenic proteins (i) are covalently linked to carrier protein molecules (ii). Also described herein is a pharmaceutical composition that comprises said immunogenic product.