发明名称 Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
摘要 Disclosed are acyl-4-carboxyphenylurea derivatives of the formula (I) including their physiologically acceptable salts. Further disclosed is a process for the production of compounds of formula (I) which comprises reacting ureas of formula (2) or aniline derivatives of the formula (3) with aroyl isocyanates, with reactive acid derivatives, with acid chlorides or with anhydrides, of the formula (4). Still further disclosed is the use of compounds of formula (I) for the production of a medicament for the treatment of type-2 diabetes or for lowering blood sugar.
申请公布号 NZ535834(A) 申请公布日期 2006.07.28
申请号 NZ20030535834 申请日期 2003.03.28
申请人 SANOFI-AVENTIS DEUTSCHLAND GMBH 发明人 DEFOSSA, ELISABETH;KADEREIT, DIETER;SCHOENAFINGER, KARL;KLABUNDE, THOMAS;BURGER, HANS-JOERG;HERLING, ANDREAS;WENDT, KARL-ULRICH;VON ROEDERN, ERICH;ENHSEN, ALFONS;REIKE-ZAPP, JOERG
分类号 C07D295/14;A61K31/196;A61K31/402;A61K31/535;A61P3/10;A61P7/12;C07C273/18;C07C275/54;C07D295/155;(IPC1-7):C07C275/54;C07D295/12;A61K31/17 主分类号 C07D295/14
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