发明名称 |
METHOD OF CONJUGATING AMINOTHIOL CONTAINING MOLECULES TO VEHICLES |
摘要 |
The present invention relates to a novel chemical process that provides novel vehicle derivatives that are exceptional 1,2- or 1,3-aminothiol specific reagents for conjugation to unprotected targeted compounds (e.g., polypeptides, peptides, or organic compounds) having or modified to have a 1,2- or 1,3 aminothiol group. The invention further relates to the methods of using novel water-soluble polymer derivatives and conjugates thereof. |
申请公布号 |
WO2006079099(A2) |
申请公布日期 |
2006.07.27 |
申请号 |
WO2006US02608 |
申请日期 |
2006.01.24 |
申请人 |
AMGEN INC.;D'AMICO, DERIN C.;ASKEW, JR., BENNY C. |
发明人 |
D'AMICO, DERIN C.;ASKEW, JR., BENNY C. |
分类号 |
A61K47/48 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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