摘要 |
The invention provides a human 5HT5a which is associated with the cardiovascular diseases, infections, gastroenterological diseases, cancer, inflammation, metabolic diseases, hematological diseases, neurological diseases, urological diseases. The invention also provides assays for the identification of compounds useful in the treatment or prevention of cardiovascular diseases, infections, gastroenterological diseases, cancer, inflammation, metabolic diseases, hematological diseases, neurological diseases, urological diseases. The invention also features compounds which bind to and/or activate or inhibit the activity of 5HT5a as well as pharmaceutical compositions comprising such compounds. |
申请人 |
BAYER HEALTHCARE AG;GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |
发明人 |
GOLZ, STEFAN;BRUEGGEMEIER, ULF;GEERTS, ANDREAS |