发明名称 Remedies with the use of hollow protein nanoparticles presenting growth factor or the like
摘要 The invention provides a disease-treating drug, specifically acting particular cells or tissues, which is based on protein hollow nanoparticles. The drug's therapeutic effects are confirmed through animal experiments. The invention also provides a treatment method using the drug. The disease-treating drug comprises a substance to be transferred into a cell for treatment of a disease (for example, cancer-treating, thymidine kinase gene of herpes simplex virus type 1) encapsulated in hollow nanoparticles containing particle-forming protein (for example, hepatitis B virus surface antigen protein modified to lose infectivity to inherent hepatocyte and also display a growth factor) displaying, for example, a growth factor.
申请公布号 US2006165726(A1) 申请公布日期 2006.07.27
申请号 US20040509248 申请日期 2004.09.28
申请人 JAPAN SCIENCE AND TECHNOLOGY AGENCY 发明人 KURODA SHUNICHI;TANIZAWA KATSUYUKI;KONDO AKIHIKO;UEDA MASAKAZU;SENO MASAHARU;IWABUKI HIDEHIKO
分类号 A61K39/29;C12N15/09;A61K9/08;A61K9/14;A61K9/50;A61K9/51;A61K38/00;A61K39/245;A61K47/42;A61K48/00;A61P1/16;A61P35/00;C07K14/02 主分类号 A61K39/29
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