The invention relates to compositions and methods for modulating the expression of apolipoprotein B, and more particularly to the downregulation of apolipoprotein B by chemically modified oligonucleotides.
申请公布号
WO2006036916(A3)
申请公布日期
2006.07.27
申请号
WO2005US34492
申请日期
2005.09.26
申请人
ALNYLAM PHARMACEUTICALS, INC.;SOUTSCHEK, JUERGEN;VORNLOCHER, HANS-PETER;HADWIGER, PHILIPP;ELBASHIR, SAYDA
发明人
SOUTSCHEK, JUERGEN;VORNLOCHER, HANS-PETER;HADWIGER, PHILIPP;ELBASHIR, SAYDA