发明名称 |
Peptide antagonists of vascular endothelial growth factor |
摘要 |
The present invention provides isolated polypeptides having VEGF antagonist activity, pharmaceutical compositions and methods of treatment. The polypeptides of the invention include polypeptides comprising a portion of SEQ ID NO: 1 having VEGF antagonist activity, polypeptides comprising SEQ ID NO: 2 or a portion thereof having VEGF antagonist activity, and a polypeptide having the structure of formula (I), set forth above. The present invention further includes analogs and derivatives of these polypeptides having VEGF antagonist activity.
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申请公布号 |
US2006166878(A1) |
申请公布日期 |
2006.07.27 |
申请号 |
US20040858849 |
申请日期 |
2004.06.02 |
申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
KLAGSBRUN MICHAEL;SOKER SHAY |
分类号 |
A61K38/17;A61K38/00;A61K38/08;A61K38/10;A61K48/00;C07K14/47;C07K14/71 |
主分类号 |
A61K38/17 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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