<p>The invention relates to improved means for preventing eversion and subsequent obstruction of thin-walled, floppy gastrointestinal liners implanted in the digestive tract of an animal. The implantable devices include an anchor (705) adapted for attachment within a natural body lumen and a thin-walled, floppy sleeve (710) open at both ends and defining a lumen therebetween. A substantial length of the sleeve has material characteristics that result in the sleeve being prone to eversion in the presence of retrograde pressures. Exemplary eversion-resistant features provide an increased stiffness and/or an increased friction coefficient between the anchor and the proximal end of the sleeve to resist eversion. In some embodiments, the eversion-resistant feature includes an ant i -buckling element, such as a wire coupled along the substantial length of the sleeve.</p>
申请公布号
WO2006078927(A1)
申请公布日期
2006.07.27
申请号
WO2006US02073
申请日期
2006.01.18
申请人
GI DYNAMICS, INC.;LEVINE, ANDY, H.;MELANSON, DAVID, A.;PARKER, IAN