发明名称 |
Process for producing optically active 3-hydroxypropionic ester derivative |
摘要 |
The present invention is to provide a process for simply producing an optically active 3-hydroxypropionic ester derivative useful as a medicament intermediate from an inexpensive material. More specifically, the present invention is directed to a process for producing an optically active 3-hydroxypropionic ester derivative comprising reacting an acetic ester derivative available at low cost with abase and a formic ester, thereby converting the acetic ester derivative into a 2-formylacetic ester derivative, and thereafter, stereospecifically reducing the formyl group of the derivative by use of an enzymatic source capable of stereoselectively reducing the formyl group of the derivative.
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申请公布号 |
US2006166342(A1) |
申请公布日期 |
2006.07.27 |
申请号 |
US20050536768 |
申请日期 |
2005.05.27 |
申请人 |
TAOKA NAOAKI;MORIYAMA DAISUKE;MORI KOHEI;OISHI TAKAHIRO |
发明人 |
TAOKA NAOAKI;MORIYAMA DAISUKE;MORI KOHEI;OISHI TAKAHIRO |
分类号 |
C12P7/62;C07C67/313;C07D317/60;C12P17/04;C12P41/00 |
主分类号 |
C12P7/62 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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