发明名称 |
HOCHGRADIG LIPOPHILE CAMPTOTHECIN-DERIVATE |
摘要 |
This invention relates to novel derivatives of camptothecin, and will, particularly to derivatives having a substitution at the C-7 position, or at one of the C-9, C-10, C-11 or C-12 positions, or to disubstituted derivatives having a first substitution at C-7 and a second at one of C-9, C-10, C-11 or C-12. The invention also includes methods of using the compounds as Topoisomerase I inhibitors to treat patients with cancer. The invention also includes pharmaceutical formulations which consist of the novel compounds in solution or suspension with one or more pharmaceutical excipients or diluents. |
申请公布号 |
DE69834923(D1) |
申请公布日期 |
2006.07.27 |
申请号 |
DE1998634923 |
申请日期 |
1998.02.11 |
申请人 |
BIONUMERIK PHARMACEUTICALS, INC. |
发明人 |
HAUSHEER, H.;HARIDAS, KOCHAT;SEETHARAMULU, P.;REDDY, G.;YAO, SHIJIE;PETLURU, N.;MURALI, DHANABALAN |
分类号 |
C07D209/56;A01N43/42;A61K31/4738;A61P35/00;A61P35/02;C07D487/00;C07D491/00;C07D491/22;C07D495/00;C07F7/08 |
主分类号 |
C07D209/56 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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