发明名称 |
Process for the preparation of pharmaceutical composition containing antiretroviral protease inhibitor with improve bioavalability |
摘要 |
The present invention provides process for manufacturing antiretroviral protease inhibitor (saquinavir, indinavir, nelfinavir,lopinavir,amprenavir) with improved bioavailability by incorporating Piperine. The quantity of Piperine required for this purpose ranges up to 30 mgm per dosage form to be administered. The pharmaceutical compositions incorporating piperine may be prepared in the form of liquid, powder, capsule or tablet or any other desired dosage form. The improved bioavailability of the drug is helpful in reducing the amount of the drug to be consumed as well as no. and or frequency of dosage form to be consumed. This helps in improving compliance of patient. |
申请公布号 |
ZA200408929(B) |
申请公布日期 |
2006.07.26 |
申请号 |
ZA20040008929 |
申请日期 |
2004.11.04 |
申请人 |
MODI, INDRAVADAN, A.;KHAMAR, BAKULESH, M. |
发明人 |
KHAMAR, BAKULASH, M. |
分类号 |
A61K;A61K31/472;A61K31/4725;A61K31/496;A61K31/505;A61K31/635;A61P31/18 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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