| 摘要 |
The present invention features hydrogel drug delivery systems and methods of producing and using such systems for the treatment of wounds. The systems are based on a hydrogel into which a low concentration of growth factor, e.g., epidermal growth factor, is passively transferred from a dilute aqueous solution. When placed in contact with a wounded tissue, the growth factor passively transfers out of the contact lens to provide accelerated healing. The amount of growth factor absorbed into the hydrogel is low, e.g., <=350 ppb, but this amount has surprisingly been found to be effective in producing a therapeutic effect. The systems are applicable to ocular and other wound treatments. |
