| 发明名称 |
3,4,-Disubstituted pyrroles and their use in treating inflammatory diseases |
| 摘要 |
This invention provides novel substituted 3-(2,5-disubstituted)pyridyl-4-aryl pyrroles, and pharmaceutical compositions comprising same, useful for treating disorders ameliorated by reducing TNF-alpha production and/or p38 activity in appropriate cells. This invention also provides therapeutic and prophylactic methods using the instant pharmaceutical compositions. |
| 申请公布号 |
ZA200503383(B) |
申请公布日期 |
2006.07.26 |
| 申请号 |
ZA20050003383 |
申请日期 |
2005.04.26 |
| 申请人 |
JANSSEN PHARMACEUTICA N.V. |
发明人 |
BULLINGTON, JAMES, J.;JACKSON, PAUL, F.;XIAODONG FAN;YUE-MEI ZHANG |
| 分类号 |
A61K;C07D;C07D401/04;C07D401/14;C07D403/04;C07D413/14;C07D471/04;C07D487/04 |
主分类号 |
A61K |
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