发明名称 |
Process for preparing 1,2,3,9-tetrahydro-9-3-Ä(2-methyl-1H-imidazol-1-yl)methylÜ-4H-Carbazol-4-one |
摘要 |
A process for preparing ondansetron by transamination of an ondansetron structural analog that can be readily prepared conveniently by a Mannich reaction is provided. The process represents an improvement upon known procedures for making ondansetron by transamination because of its rapid rate, selectivity and the ease with which the product can be isolated from the reaction mixture. |
申请公布号 |
ZA200408934(B) |
申请公布日期 |
2006.07.26 |
申请号 |
ZA20040008934 |
申请日期 |
2004.11.04 |
申请人 |
TEVA CRYOGYSZERGYAR RESZVENYTARSASAG |
发明人 |
SANDOR MOLNAR;CSABA SZABO;MAZAROS, SOS, E.;SZABOLCS SALYI;TIVADAR TAMAS |
分类号 |
A61K;A61K31/4178;A61P;A61P1/08;C07D;C07D209/88;C07D403/06 |
主分类号 |
A61K |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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