发明名称 Organic compounds with biological activity as thrombin inhibitors and use thereof
摘要 The invention relates to biologically active molecules, interacting with thrombin and inhibiting the same. The invention particularly relates to molecules of general formula:Y<SUP>1</SUP>-(NH-X<SUP>1</SUP>-C-O)-(NH-X<SUP>2</SUP>-C-C)-(NH-X<SUP>3</SUP>-C-O)NH-X<SUP>4</SUP>-C-O)-(NH-X<SUP>5</SUP>-C-O)-(NH-X<SUP>6</SUP>-C-O)-Y<SUP>2</SUP>, in which Y<SUP>1</SUP>, Y<SUP>2</SUP>, and X<SUP>1-6 </SUP>have the meanings given in the description, N or C-terminal shortened variants of said compounds and the use thereof for the production of medicaments.
申请公布号 US7081447(B2) 申请公布日期 2006.07.25
申请号 US20040798218 申请日期 2004.03.10
申请人 NOVEL SCIENCE INTERNATIONAL GMBH 发明人 THURK MARCEL
分类号 A61K38/08;A61K38/07;C07K1/00;C07K5/10;C07K7/04;C07K7/06 主分类号 A61K38/08
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