发明名称 |
PROCESS FOR PREPARING 1,2,3,9-TETRAHYDRO-9-METHYL-3-METHYLENE-4H- CARBAZOL-4-ONE AND ONDANSETRON THEREFROM |
摘要 |
The present invention provides a rapid, high-yielding process for preparing 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one from 1,2,3,9-tetrahydro-9-methyl-4H-carbazol-4-one without using a secondary amine as a catalyst, and without using glacial acetic acid as a solvent. The present invention further provides a rapid, high-yielding process for preparing ondansetron from 1,2,3,9-tetrahydro-9-methyl-3-methylene-4H-carbazol-4-one without using alumina as a catalyst.
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申请公布号 |
WO2006018846(A3) |
申请公布日期 |
2006.07.20 |
申请号 |
WO2005IL00893 |
申请日期 |
2005.08.17 |
申请人 |
TARO PHARMACEUTICAL INDUSTRIES LTD.;GUTMAN, DANIELLA;CYJON, ROSA |
发明人 |
GUTMAN, DANIELLA;CYJON, ROSA |
分类号 |
C07D233/04;A61K31/415;C07D403/10 |
主分类号 |
C07D233/04 |
代理机构 |
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主权项 |
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地址 |
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