发明名称 |
Compounds for delivering amino acids or peptides with antioxidant activity into mitochondria and use thereof |
摘要 |
Disclosed are compounds containing single amino acids, peptides, or derivatives thereof which are selectively delivered to the mitochondria of a cell. Compounds of the invention exhibit antioxidant activity thereby reducing reactive oxygen species in cells. These compounds are useful for inhibiting oxidative stress-induced cell injury or death both in vivo and ex vivo. In addition, methods for the synthesis of these compounds are disclosed.
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申请公布号 |
US2006160748(A1) |
申请公布日期 |
2006.07.20 |
申请号 |
US20050312873 |
申请日期 |
2005.12.20 |
申请人 |
SHEU SHEY-SHING;ANDERS MARION W;XU LIN;SHARMA VIRENDRA K;NAUDURI DHANANJAYA |
发明人 |
SHEU SHEY-SHING;ANDERS MARION W.;XU LIN;SHARMA VIRENDRA K.;NAUDURI DHANANJAYA |
分类号 |
A61K38/05;A61K31/198 |
主分类号 |
A61K38/05 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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