发明名称 |
Alkynyl-containing tryptophan derivative inhibitors of tace/matrix metalloproteinase |
摘要 |
This invention provides compounds of Formula I, having the structure: that are useful in treating diseases or disorders mediated by TNF-alpha. The invention further provides methods for use of the compounds for treating such a disease or disorder or for alleviating symptoms thereof.
|
申请公布号 |
US2006160884(A1) |
申请公布日期 |
2006.07.20 |
申请号 |
US20050318701 |
申请日期 |
2005.12.27 |
申请人 |
WYETH |
发明人 |
PARK KAAPJOO;LEVIN JEREMY I.;GOPALSAMY ARIAMALA |
分类号 |
A61K31/405;C07D209/18;C07D407/02 |
主分类号 |
A61K31/405 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|