发明名称 |
THERAPEUTIC AGENT FOR CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD), CYSTIC FIBROSIS OR PULMONARY HYPERTENSION |
摘要 |
<p>A preventive, therapeutic or improving agent for chronic obstructive pulmonary disease (COPD), cystic fibrosis or pulmonary hypertension is provided. More specifically, the invention is directed to (1) a preventive, therapeutic or improving agent for chronic obstructive pulmonary disease (COPD), cystic fibrosis or pulmonary hypertension comprising an NF-?B decoy as an active ingredient; (2) the NF-?B decoy being an oligonucleotide having a binding sequence GGGRHTYYHC (wherein R represents A or G, Y represents C or T, and H represents A, C or T); (3) the oligonucleotide in which the NF-?B binding sequence is GGGATTTCCC or GGGACTTTCC; (4) the NF-?B decoy being the oligonucleotide represented by SEQ ID NO: 3; (5) the NF-?B decoy being a double-stranded oligonucleotide; (6) the NF-?B decoy being administrated in the form of a fine powder; and (7) the NF-?B decoy fine powder being a dry powder.</p> |
申请公布号 |
WO2006075776(A1) |
申请公布日期 |
2006.07.20 |
申请号 |
WO2006JP300665 |
申请日期 |
2006.01.12 |
申请人 |
ANGES MG, INC.;OTSU, KUNIMIKI;SAITO, TETSU;GEMBA, TAKEFUMI |
发明人 |
OTSU, KUNIMIKI;SAITO, TETSU;GEMBA, TAKEFUMI |
分类号 |
A61K45/00;A61K9/14;A61K9/72;A61K31/7088;A61K31/713;A61K48/00;A61P11/00;C12N15/09 |
主分类号 |
A61K45/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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