The present invention relates to prodrugs of dihydropyrazole compounds that are useful for treating cellular proliferative diseases, for treating disorders associated with KSP kinesin activity, and for inhibiting KSP kinesin. The invention also related to compositions which comprise these compounds, and methods of using them to treat cancer in mammals.
申请公布号
WO2006007497(A3)
申请公布日期
2006.07.20
申请号
WO2005US22879
申请日期
2005.06.27
申请人
MERCK & CO., INC.;COLEMAN, PAUL, J.;COX, CHRISTOPHER, D.;HARTMAN, GEORGE, D.
发明人
COLEMAN, PAUL, J.;COX, CHRISTOPHER, D.;HARTMAN, GEORGE, D.