发明名称 |
VORRICHTUNG UND VERFAHREN ZUM ELEKTRISCHEN KONTAKTIEREN VON IN EINER FLÜSSIGKEIT IN SUSPENSION BEFINDLICHEN BIOLOGISCHEN ZELLEN |
摘要 |
<p>An apparatus for electrically contacting biological cells suspended in a liquid has a substrate having at least one opening and an electrode for electrically contacting a cell immobilized above the opening. A contact unit with a contact tip is arranged below said opening. A top end of the contact tip projects into the opening in such a way that it comes to bear against a cell membrane of the immobilized cell. The contact tip has a contact channel which ends at its top end. A hydrodynamic low pressure can be exerted upon the cell membrane via the contact channel, and the electrode is electrically connected to the contact channel. In a method for electrically contacting biological cells suspended in a liquid, a cell is immobilized above an opening provided in a substrate, and the immobilized cell is contacted via at least one electrode. For contacting the immobilized cell, a hydrodynamic low pressure is generated acting on a cell membrane through a contact tip projecting into the opening.</p> |
申请公布号 |
DE50110063(D1) |
申请公布日期 |
2006.07.20 |
申请号 |
DE2001510063 |
申请日期 |
2001.07.05 |
申请人 |
NMI NATURWISSENSCHAFTLICHES UND MEDIZINISCHES INSTITUT AN DER UNIVERSITAET TUEBINGEN |
发明人 |
STETT, ALFRED;HAEMMERLE, HUGO;NISCH, WILFRIED;KNOTT, THOMAS |
分类号 |
C12M1/34;G01N33/483;C12Q1/02;G01N1/00;G01N27/28;G01N27/30;G01N27/327;G01N27/416;G01N33/15;G01N33/487;G01N33/50;G01N33/543;G01N37/00 |
主分类号 |
C12M1/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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