发明名称 METHOD FOR STABLE CELL TRANSDUCTION BY VIRAL VECTORS
摘要 FIELD: biotechnology. ^ SUBSTANCE: invention relates to method for stable cell transduction of hematopoesis system or hematopoesis stem cells. Claimed method includes simultaneous cell in vivo or in vitro contact with lentivirus vector and molecule bonding to cell surface. Method of present invention allows stable transduction more 75 % of cells over 14 days. Method for introduction of gene material into cell also is disclosed. ^ EFFECT: new method useful in medicine, virology, and gene engineering. ^ 40 cl, 28 dwg, 9 ex
申请公布号 RU2280074(C2) 申请公布日期 2006.07.20
申请号 RU20030108736 申请日期 2001.08.29
申请人 VIREHKSSIS KORPOREJSHN 发明人 JUMO LORAN;KHAN VEJ;LU KSIAOBIN;SLEPUSHKIN VLADIMIR;LESHER MISHELL';DEHVIS BRAJAN;CHANG JUNG-NIEN;DROPULIK BORO
分类号 C12N5/00;C12N15/09;A61K48/00;C12N1/15;C12N1/19;C12N1/21;C12N5/08;C12N5/10;C12N7/00;C12N15/63;C12N15/867 主分类号 C12N5/00
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