发明名称 |
MODULATION OF IL-5 AND IL-MEDIATED CELL RESPONSES |
摘要 |
FIELD: immunology. ^ SUBSTANCE: invention relates to preparation of composition containing agent targeted to interleukin-15 (IL-5) receptor as the first active ingredient and agent targeted to interleukin-2 (IL-2) receptor as the second active ingredient; as well as methods for immune response suppression. Said compositions are useful in combined therapy: two or more agent which advance T-cell death or at least one agent which inhibits T-cell proliferation. ^ EFFECT: immunotherapy of increased effectiveness. ^ 34 cl, 13 dwg |
申请公布号 |
RU2280255(C2) |
申请公布日期 |
2006.07.20 |
申请号 |
RU20030110571 |
申请日期 |
2001.09.14 |
申请人 |
BET IZREJEHL DIKONISS MEDIKAL SENTER, INK. |
发明人 |
LI SJAN' CHAN;STROM TERRI;CHZHEHN SIN' SJAO |
分类号 |
C12N15/09;G01N33/53;A61K31/436;A61K38/00;A61K38/20;A61K39/395;A61K45/00;A61P1/00;A61P3/10;A61P5/14;A61P5/30;A61P17/00;A61P17/06;A61P19/02;A61P19/04;A61P19/08;A61P21/00;A61P21/04;A61P25/00;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/06;A61P43/00;C07K14/54;C07K14/55;C12N5/06;C12Q1/02 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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