| 发明名称 |
Method of producing 1-hydroxy-1,1-diphosphonic acid compounds |
| 摘要 |
In a method for preparing 1-hydroxy-1,1-diphosphonic acid compounds of the general formula I and/or of their pharmacologically compatible salts a compound of the formula II is reacted with a compound P(OSiR<SUP>5</SUP><SUB>3</SUB>)<SUB>3-p</SUB>R<SUP>6</SUP><SUB>p </SUB>and the reaction product is hydrolyzed.
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| 申请公布号 |
US7078393(B2) |
申请公布日期 |
2006.07.18 |
| 申请号 |
US20030471828 |
申请日期 |
2003.09.15 |
| 申请人 |
EUCRO EUROPEAN CONTRACT RESEARCH GMBH & CO. KG |
发明人 |
BLUM HELMUT;GREB WOLFGANG;PUSTOVIT YURII;ROESCHENTHALER GERD-VOLKER |
| 分类号 |
A61K31/66;C07F7/18;C07F9/28;C07F9/38;C07F9/40 |
主分类号 |
A61K31/66 |
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