| 发明名称 |
Aggrecanase molecules |
| 摘要 |
Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.
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| 申请公布号 |
US7078217(B2) |
申请公布日期 |
2006.07.18 |
| 申请号 |
US20030354983 |
申请日期 |
2003.01.31 |
| 申请人 |
WYETH |
发明人 |
CORCORAN CHRISTOPHER J.;AGOSTINO MICHAEL J.;LAVALLIE EDWARD R.;FLANNERY CARL R.;COLLINS-RACIE LISA A. |
| 分类号 |
C12N9/64;C12N15/09;A61K39/395;A61K45/00;A61P1/00;A61P1/02;A61P1/04;A61P7/00;A61P9/00;A61P11/00;A61P11/06;A61P13/00;A61P17/02;A61P19/00;A61P19/02;A61P19/10;A61P25/00;A61P25/02;A61P25/06;A61P25/14;A61P25/16;A61P25/24;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07H21/04;C07K16/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N5/22;C12P21/02;C12Q1/37 |
主分类号 |
C12N9/64 |
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