发明名称 |
Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood GLP-1 level |
摘要 |
The present invention concerns combination of an amount of a GPR119 agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor such that the combination provides an effect in lowering a blood glucose level or in increasing a blood GLP-1 level in a subject over that provided by the amount of the GPR119 agonist or the amount of the DPP-IV inhibitor alone and the use of such a combination for treating or preventing diabetes and conditions related thereto or conditions ameliorated by increasing a blood GLP-1 level. The present invention also relates to the use of a G protein-coupled receptor to screen for GLP-1 secretagogues.
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申请公布号 |
US2006154866(A1) |
申请公布日期 |
2006.07.13 |
申请号 |
US20060328405 |
申请日期 |
2006.01.09 |
申请人 |
CHU ZHI-LIANG;LEONARD JAMES N;AL-SHAMMA HUSSIEN A;JONES ROBERT M |
发明人 |
CHU ZHI-LIANG;LEONARD JAMES N.;AL-SHAMMA HUSSIEN A.;JONES ROBERT M. |
分类号 |
A61K38/26;A61K38/04;C12Q1/68;G01N33/53 |
主分类号 |
A61K38/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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