发明名称 |
COMPOUNDS, COMPOSITIONS AND METHODS OF INHIBITING A-SYNUCLEIN TOXICITY |
摘要 |
Compounds and compositions are provided for treatment or amelioration of one or more symptoms of a-synuclein toxicity, a-synuclein mediated diseases or diseases in which a-synuclein fibrils are a symptom or cause of the disease. In one embodiment, the compounds for use in the compositions and methods are heteroaryl acylguanidines, heteroarylhydrazones, dihydropyridones, heteroaryl and aryl styryl ketones, and heteroarylpyrazoles. |
申请公布号 |
WO2006034003(A3) |
申请公布日期 |
2006.07.13 |
申请号 |
WO2005US33050 |
申请日期 |
2005.09.16 |
申请人 |
WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH;FOLDRX PHARMACEUTICALS, INC.;LINDQUIST, SUSAN, L.;OUTEIRO, TIAGO;LABAUDINIERE, RICHARD |
发明人 |
LINDQUIST, SUSAN, L.;OUTEIRO, TIAGO;LABAUDINIERE, RICHARD |
分类号 |
A61K31/425;A61K31/415;A61K31/42;A61K31/44 |
主分类号 |
A61K31/425 |
代理机构 |
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